Silicone in Pharmaceutical

Silicones are known for their excellent biocompatibility and are widely used as active ingredients, antifoaming agents, and excipients for pharmaceutical applications. They are used to relieve the painful symptoms of gas in the stomach and intestines and also treat the symptoms of stomach acid, such as stomach upset, heartburn, and acid indigestion. Silicones as excipients support the design of pharmaceutical formulations and are crucial for drug delivery within the body; they deliver foam control and lubrication and facilitate the physiological absorption of the drug. In which, Simethicone USP and IP emulsions at different concentrations are incorporated in gastrointestinal medicaments and antacid products, and Dimethicone is used as an excipient in topical medicated preparations.

Applications:

Gastrointestinal Disorders

Syrups and Suspensions

Hard and Chewable Tablets

Powders

Gastrointestinal Disorders

Syrups and Suspensions

Hard and Chewable Tablets

Powders

Antacid Products

Syrups

Dispersible Tablets

Soft Gel Capsules

Antacid Products

Syrups

Dispersible Tablets

Soft Gel Capsules

Excipients

Skin Protecting Cream

Topical Medicated Ointments & Gels

Personal Lubricants

Excipients

Skin Protecting Cream

Topical Medicated Ointments & Gels

Personal Lubricants

Pharmaceutical Product Series

Fluid Product Range

ProductViscosity 25 °C (cps)Volatile ContentTypeRI
LK- SIL 100D200, 350, 1000<0.3%Dimethicone base for formulations, lubrication~1.406
Dimethicone200, 350, 1000 BP<0.3%Dimethicone base for formulations, lubrication~1.406

Defoaming Products

ProductCertificationActive ProductTypeClear-spot time
SimethiconeIP, USP100%Silica-Dimethicone defoaming compound6-15 Sec
Simethicone 30%IP, USP30%Silica- Dimethicone defoaming emulsion6-15 Sec

Fluid Product Range

LK- SIL 100D

Viscosity 25 °C (cps): 200, 350, 1000
Volatile Content: <0.3%
Type: Dimethicone base for formulations, lubrication
RI: ~1.406

Dimethicone

Viscosity 25 °C (cps): 200, 350, 1000 BP
Volatile Content: <0.3%
Type: Dimethicone base for formulations, lubrication
RI: ~1.406

Defoaming Products

Simethicone

Certification: IP, USP
Active Product: 100%
Type: Silica-Dimethicone defoaming compound
Clear-spot time: 6-15 Sec

Simethicone 30%

Certification: IP, USP
Active Product: 30%
Type: Silica- Dimethicone defoaming emulsion
Clear-spot time: 6-15 Sec

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